منابع مشابه
Deleterious consequences of allogeneic blood transfusion on postoperative infection: really a transfusion-related immunomodulation effect?
The purported deleterious effect of transfusion-related immunomodulation (TRIM) on postoperative infection and its prevention by leukoreduction of transfused blood are a matter of great controversy among transfusion medicine specialists. In a recent review on this issue,1 Vamvakas and Blajchman pointed out that current evidence supporting a beneficial effect of leukoreduction is inconclusive be...
متن کاملDeleterious consequences of allogenic blood transfusion on postoperative infection: really a transfusion-related immunomodulation effect?
The purported deleterious effect of transfusion-related immunomodulation (TRIM) on postoperative infection and its prevention by leukoreduction of transfused blood are a matter of great controversy among transfusion medicine specialists. In a recent review on this issue,1 Vamvakas and Blajchman pointed out that current evidence supporting a beneficial effect of leukoreduction is inconclusive be...
متن کاملDisseminated fusariosis and endogenous fungal endophthalmitis in acute lymphoblastic leukemia following platelet transfusion possibly due to transfusion-related immunomodulation
BACKGROUND To report a case of disseminated fusariosis with endogenous endophthalmitis in a patient with acute lymphoblastic leukemia. Transfusion-associated immune modulation secondary to platelet transfusion could play an important role in the pathophysiology of this case. CASE PRESENTATION A 9 year-old male with acute lymphoblastic leukemia complicated by pancytopenia and disseminated Intr...
متن کاملTransfusion-Associated Immunomodulation: Experimental Facts and Clinical Reality New Perspectives
Blood component transfusion may be required in association with emergency and chronic disease to improve hemodynamics and tissue oxygenation. Due to the risk of microbial transfection from donor to recipient, the blood is undergoing vigorous testing to improve safety. It is well known, however, that blood component transfusion may lead to certain acute side effects with a frequency of 0.5–2% de...
متن کاملTransfusion immunomodulation or TRIM: what does it mean clinically?
Evidence from a variety of sources indicate that allogeneic blood transfusions can induce clinically significant immunosuppression, as well as other effects, in recipients. This clinical syndrome is generally referred to in the Transfusion Medicine literature as transfusion-associated immunomodulation, or TRIM. TRIM has been linked to an improved clinical outcome in the setting of renal allogra...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Transfusion Alternatives in Transfusion Medicine
سال: 2002
ISSN: 1295-9022,1778-428X
DOI: 10.1111/j.1778-428x.2002.tb00060.x